March 14, 2026
By Jay Chowdappa, MD, co-founder and CEO, Zynix AI · Updated October 1, 2026
Zynix AI has passed 1M+ value-based care patients onboarded, with customer organizations in 30 states that range from ACOs to independent practices and FQHCs. The milestone reflects demand for AI infrastructure and workflows for value-based care: agents that run outreach, scheduling, reminders and follow-up within each team's rules, while clinicians keep clinical decisions.
Zynix AI has reached a transformative milestone: over one million value-based care (VBC) patients are now onboarded across its platform, with customer organizations in 30 states. This achievement underscores the growing demand for AI-powered solutions that go beyond surface-level analytics to deliver actionable care execution that care teams direct.
From Accountable Care Organizations (ACOs) participating in the Medicare Shared Savings Program (MSSP) to independent practices and Federally Qualified Health Centers (FQHCs), Zynix AI's platform has proven its ability to scale across diverse healthcare settings. The platform's AI agents — including ZynSchedule, ZynAfterHours and the chronic care management agent — run outreach, scheduling, reminders, after-hours calls and follow-up within the rules and hours each care team sets.
Customer organizations use the Zynix platform for the follow-up work their programs depend on, and the mix differs by type of organization.
ACOs use it for post-discharge follow-up, annual wellness visit outreach and care gap outreach across their participating practices. A Medicare Advantage health plan uses it for member outreach and care management, and a hospital system for post-discharge outreach, after-hours access and physician-reviewed documentation. A community health center uses it for after-hours access and preventive outreach in the languages its patients speak, and a multi-site physician group for scheduling and reminders that keep visits on schedule.
Each organization's own story, with what its leaders have said on the record, is on the Zynix customer stories page.
Unlike traditional health IT solutions that surface recommendations for human action, Zynix AI's agents carry out the outreach, scheduling and follow-up steps of each care plan, within the rules and hours the care team sets, and escalate to staff by rule. When a patient is discharged from the hospital, the transitions of care agent starts outreach when the discharge alert arrives and books the follow-up visit, while licensed clinical staff make the Transitional Care Management (TCM) interactive contact that CMS requires within 2 business days of discharge. When care gaps are identified, the preventive and quality activation agent runs targeted outreach to book the screenings and visits that close HEDIS and STARS quality measure gaps, and routes clinical questions to the care team.
At the core of Zynix AI's platform is ZynixLLM, its language model layer. It supports the agents' outreach, scheduling, reminders and documentation prep, and the escalation rules each care team sets decide when a clinician steps in.
As a SOC 2 Type II audited company with HIPAA-aligned safeguards (BAA available) and customer organizations in 30 states, Zynix AI is positioned to continue its rapid growth trajectory. The company is actively expanding its agent capabilities and deepening integrations with EHR systems, claims platforms, and health plan networks.
Zynix AI builds AI infrastructure and workflows for value-based care. The Zynix platform connects claims, EHR and ADT data, identifies the patients and care gaps that need attention, and helps care teams follow through with care plans, outreach agents and ambient documentation. Agents handle outreach, scheduling, reminders and documentation prep, and clinicians make the clinical decisions. It serves ACOs, MSOs and IPAs, health plans and FQHCs.
No. Agents work within the rules and hours each care team sets and escalate to staff by rule; they do not diagnose, triage clinically or recommend treatment. Symptom questions go to the on-call clinician, licensed clinical staff own clinical judgment, and ZynScribe notes stay drafts until a physician reviews and approves them. The AI agents overview shows which work each agent family takes on and where the care team steps in.
For TCM (CPT 99495 and 99496), CMS requires an interactive contact with the patient or caregiver within 2 business days of discharge, made by the practitioner or by clinical staff who can address needs beyond scheduling, and a face-to-face visit within 7 or 14 calendar days, depending on complexity. Agents support the work around it: outreach from the discharge alert, repeat attempts for hard-to-reach patients, booking the visit and routing clinical questions. Licensed staff make the billable contact.
Zynix AI is SOC 2 Type II audited, and the report is available on request. It uses HIPAA-aligned safeguards, offers a business associate agreement (BAA), and has HITRUST CSF certification in progress. When you evaluate any vendor that will handle protected health information, ask for its latest SOC 2 Type II audit report and a signed BAA, and ask how that information is stored, encrypted, retained and accessed.
Named EHR connections include Epic, Oracle Health (Cerner), athenahealth, eClinicalWorks, NextGen, Allscripts, Greenway and DrChrono, alongside claims, ADT, lab and pharmacy data. Connections use standard formats: FHIR, HL7 v2 messages, C-CDA documents, X12 transactions, Medicare CCLF and BCDA files, and NCPDP for pharmacy. Which interface is used depends on the EHR and on how each organization has it set up.
CMS: Transitional Care Management Services (MLN booklet MLN908628, August 2025). https://www.cms.gov/files/document/mln908628-transitional-care-management-services.pdf
Jay Chowdappa, MD is co-founder and CEO of Zynix AI. He is a physician, and ACOs led by him generated $300M+ in shared savings before he started Zynix AI to help care teams follow through on what their data already shows.
To learn more about how Zynix AI can transform your value-based care operations, request a demo today.